Comparing Functional Mushroom Extracts

Each medicinal mushroom offers a distinct profile of bioactive compounds and functional benefits. This comparison highlights where the strongest research support currently sits, helping you understand how different extracts may support the body in different ways.

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How to read this table

Evidence levels reflect a combination of human clinical research, preclinical studies, and traditional use.
Dots represent the relative strength of scientific support, combining human trials, traditional use, and preclinical research.
This comparison reflects current scientific research, combining human clinical data and traditional use where appropriate, with an emphasis on immune, cognitive, metabolic, and adaptogenic functions.
Functional overlap exists between many medicinal mushrooms. This comparison highlights primary areas of research focus, not exclusive effects

Research into medicinal mushrooms is ongoing. Evidence levels reflect a combination of human studies, preclinical research, and traditional use, and are not intended to diagnose or treat disease.

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Benefit / Function	Cordyceps	Reishi	Chaga	Turkey Tail	Lion’s Mane
Immune modulation	●●	●●●	●●	●●●	●●
Anti-inflammatory / antioxidant	●●	●●●	●●●	●●	●●
Energy & exercise performance	●●	●	—	—	—
Adjunc support in cancer care*	—	●	●●	●●●	—
Cardiovascular / cholesterol support	●	●	●●	●●	—
Blood sugar / metabolic support	—	●	●●	●●	—
Liver support / detox pathways	●	●	●	—	—
Mood, stress & fatigue	●●	●●	—	—	●●
Gut health / prebiotic effects	—	—	●●	●●●	●●
Cognitive / neuroprotection	—	—	—	—	●●●
Antiviral activity (mechanistic)	—	●	●	●●	—

Evidence key:

●●● Strong – Supported by human clinical data and mechanistic evidence
●● Moderate – Some human data with strong preclinical support
● Emerging – Primarily preclinical or small human studies
— Insufficient – Not enough evidence to support a claim

*Adjunct immune support refers to immune modulation alongside conventional care — not treatment or cure of disease.

Learn about the varieties

mycobio mushroom extracts

Each functional mushroom has a distinct role.

From Lion’s Mane for cognitive clarity, to Reishi for stress and recovery, Chaga for antioxidant support, Turkey Tail for immune balance, and Cordyceps for energy and performance, each variety is defined by its unique bioactive compounds and traditional use.

This guide explores how these mushrooms differ, where they fit, and how to choose the right extract for your needs.

See comparison table

Lion's Mane

Learn About Lion's Mane

Traditionally used to support cognitive clarity and focus. Often chosen for routines centred on mental performance and long-term neurological wellbeing.

Learn about Lion's Mane

Reishi

Learn About Reishi

Historically valued for its role in supporting balance and resilience. Commonly included in wellbeing routines focused on stress, recovery, and immune support.

Learn about Reishi