Lion’s Mane Mushroom & Brain health: 7 ways it can help.

Lion’s mane mushroom (Hericium erinaceus) has garnered significant attention for its potential to enhance brain health, drawing from centuries of use in traditional medicine and a growing body of modern research. This large, shaggy white fungus, named for its resemblance to a lion’s mane, is rich in bioactive compounds that may offer a range of cognitive and neurological benefits[1][11].

1. Key Bioactive Compounds and Their Effects

The primary compounds believed to drive lion’s mane’s brain benefits are hericenones and erinacines. These substances can stimulate the production of nerve growth factor (NGF), a protein essential for the growth, maintenance, and survival of neurons[1][3][4]. Notably, erinacines have been shown to cross the blood-brain barrier in animal studies, allowing them to directly influence brain tissue and promote nerve regeneration[4].

2. Neuroprotection and Cognitive Enhancement

Research suggests that lion’s mane may help protect against neurodegenerative diseases such as Alzheimer’s. Animal studies have demonstrated that lion’s mane extracts can reduce symptoms of memory loss and prevent neuronal damage caused by amyloid-beta plaques, which are closely associated with Alzheimer’s disease[1][6][9]. In a 2020 human study, participants with mild Alzheimer’s who took 1 gram of lion’s mane daily for 49 weeks showed significant improvements in cognitive test scores compared to those given a placebo[1].

A separate study involving older adults with mild cognitive impairment found that those taking lion’s mane supplements for 16 weeks performed better on cognitive tests than those on placebo. However, when supplementation stopped, their scores declined, suggesting continuous use may be necessary to maintain benefits[7].

3. Brain Cell Growth and Memory

Recent laboratory research has provided further insight into how lion’s mane may bolster brain function. Studies have shown that extracts from the mushroom can double the growth of neurons and encourage the formation of new connections between brain cells[6][9][11]. Using advanced imaging, scientists observed that lion’s mane compounds increase the size of neuronal growth cones, which are crucial for establishing new neural pathways[9][11]. This enhanced connectivity is believed to underlie improvements in memory and learning.

4. Mood, Stress, and Mental Wellbeing

Beyond cognitive function, lion’s mane may also support mental health. In a study of Japanese women experiencing menopausal symptoms, those who consumed lion’s mane extract reported lower levels of anxiety and depression compared to a placebo group[3]. The mushroom’s impact on NGF and its anti-inflammatory properties are thought to contribute to these mood-enhancing effects[3][5][8].

A pilot study in healthy young adults found that a single dose of lion’s mane improved cognitive performance speed, while a 28-day regimen showed a trend toward reduced subjective stress[5][8]. Though these results are promising, the studies were small, and larger trials are needed to confirm these effects.

5. Nerve Regeneration and Recovery

Lion’s mane’s ability to promote nerve regeneration extends beyond the brain. Animal studies indicate that its compounds may aid in the recovery from nerve injuries and could have potential applications in conditions such as stroke, Parkinson’s disease, and multiple sclerosis[3][4]. The mushroom’s unique ability to stimulate NGF production sets it apart from many other natural remedies, as NGF is vital for both new and mature nerve cells[3][4].

6. Mechanisms: Anti-Inflammatory and Antioxidant Actions

Chronic inflammation and oxidative stress are linked to cognitive decline and neurodegenerative diseases. Lion’s mane exhibits anti-inflammatory and antioxidant properties, which may help protect brain cells from damage and support overall brain health[7][9]. By reducing inflammation, lion’s mane could help maintain the integrity of neural networks and promote a healthier brain environment.

7. Traditional Use and Modern Science

Lion’s mane has a long history in Asian traditional medicine, where it was valued for its restorative effects on the mind and nerves[1][9][11]. Modern science is now beginning to validate these uses, with studies confirming its potential to enhance brain cell growth, improve memory, and support mental wellbeing.

Safety and Considerations

Lion’s mane is generally considered safe when consumed as a food or supplement. However, most research has been conducted in animals or small human trials, so more robust studies are needed to fully understand its efficacy and long-term safety[1][5][7]. Individuals interested in trying lion’s mane should consult with a healthcare provider, especially if they have underlying health conditions or are taking other medications.

In summary, lion’s mane mushroom shows significant promise as a natural supplement for supporting brain health. Its unique compounds stimulate nerve growth, protect against cognitive decline, and may improve mood and memory. While more research is needed, especially in large human populations, the existing evidence highlights lion’s mane as a fascinating and potentially valuable tool for maintaining and enhancing brain function[1][3][9][11].

Lion’s Mane Extract 60g | +30% β-glucans | 100% pure & Organic

$60.00

Using real Lion’s Mane Hericium erinaceus, this extract has high β-Glucan content, and x12 high potency, dual extracted. This provides 60 days at 1000mg dosage per day.

In stock

Lion's Mane Extract 60g | +30% β-glucans | 100% pure & Organic quantity

Add to cart

Important: not all Lion’s Mane sold in New Zealand is the same. Learn about the fake NZ Lion’s Mane.

Sources: Lion’s Mane for Brain Health

[1] 9 Health Benefits of Lion’s Mane Mushroom (Plus Side … https://www.healthline.com/nutrition/lions-mane-mushroom

[2] The Potential Health Benefits of Lion’s Mane Mushroom for brain health – Thorne https://www.thorne.com/take-5-daily/article/the-potential-health-benefits-of-lions-mane-mushroom

[3] What Are the Health Benefits of Lion’s Mane Mushrooms? https://www.webmd.com/diet/what-are-the-health-benefits-of-lions-mane-mushrooms

[4] Lion’s Mane – LiverTox – NCBI Bookshelf https://www.ncbi.nlm.nih.gov/books/NBK599740/

[5] The Acute and Chronic Effects of Lion’s Mane Mushroom … https://pmc.ncbi.nlm.nih.gov/articles/PMC10675414/

[6] Lion’s mane mushrooms may help improve memory, boost brain cell … https://www.medicalnewstoday.com/articles/improving-memory-lions-mane-mushrooms-may-double-neuron-growth

[7] 5 Lion’s Mane Mushroom Benefits https://health.clevelandclinic.org/lions-mane-mushrooms-benefits

[8] When To Take Lions Mane: Cognitive Benefits – Novomins Nutrition https://novomins.com/blogs/news/when-to-take-lions-mane

[9] Lion’s mane mushroom shows promise in boosting brain health & cell growth https://www.popsci.com/science/brain-lions-mane-mushroom/

[10] Lion’s Mane Mushroom Benefits: A Complete Supplement Guide https://www.realmushrooms.com/lions-mane-mushroom-benefits/

[11] Latest Study Suggests Lion’s Mane Mushrooms May Boost Brain Health https://www.healthline.com/health-news/latest-study-suggests-lions-mane-mushrooms-may-boost-brain-heath

[12] More Than a Mushroom: Benefits of Lion’s Mane – Institute for Natural Medicine https://naturemed.org/the-amazing-health-benefits-of-lions-mane-mushrooms/